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eBook Quasispecies and RNA Virus Evolution: Principles and Consequences (Molecular Biology Intelligence, Unit 14) ePub

by Esteban Domingo

eBook Quasispecies and RNA Virus Evolution: Principles and Consequences (Molecular Biology Intelligence, Unit 14) ePub
Author: Esteban Domingo
Language: English
ISBN: 1587060779
ISBN13: 978-1587060779
Publisher: CRC Press; 1 edition (December 1, 2000)
Pages: 221
Category: Medicine
Subcategory: Medical
Rating: 4.9
Votes: 378
Formats: mobi doc azw docx
ePub file: 1791 kb
Fb2 file: 1725 kb

Quasispecies and RNA Virus Evolution: Principles and Consequences (Molecular Biology Intelligence Unit). Esteban Domingo, John J. Holland, Christof K. Biebricher.

Quasispecies and RNA Virus Evolution: Principles and Consequences (Molecular Biology Intelligence Unit). Download (pdf, . 8 Mb) Donate Read.

Other readers will always be interested in your opinion of the books you've read. Whether you've loved the book or not, if you give your honest and detailed thoughts then people will find new books that are right for them

Other readers will always be interested in your opinion of the books you've read. Whether you've loved the book or not, if you give your honest and detailed thoughts then people will find new books that are right for them. 1. Death of a Whaler.

Start by marking Quasispecies And RNA Virus Evolution: Principles And Consequences (Molecular Biology Intelligence, Unit 14) as Want to Read: Want to Read savin. ant to Read. Read by Esteban Domingo. This book focuses on a new aspect of RNA virology: the highly dynamic, heterogeneous and plastic nature of RNA viruses which comprise more than 75% of the viruses that have been recognized as disease agents.

Molecular Basis of Genetic Variability in RNA Viruses. The variability of genome organization, so essential for RNA virus evolution, among more than 900 plant RNA viruses (56 genera) is enormous (Gibbs et a. 1997). In fact, the potential for variation of the RNA genome is so large, that a term of quasispecies was proposed to reflect the nature of RNA virus populations (Domingo et a. 1995, Eigen, 1993, 1996; Holland et a. 1992; Moya and. Garcia-Arenal, 1995).

Evolution of RNA viruses occurs through disequilibria of collections of closely related .

Evolution of RNA viruses occurs through disequilibria of collections of closely related mutant spectra or mutant clouds termed viral quasispecies. In viral evolution there is no such a thing as a molecular clock that dictates constancy of incorporation of mutations (discussed in Viral Quasispecies Dynamics In Vivo: Long-Term Virus Evolution below).

by Esteban Domingo (Author).

Quasispecies and RNA Virus Evolution: Principles and Consequences (Molecular Biology . Quasispecies : concept and implications for virology. 14. Quasispecies and RNA virus evolution : principles and consequences.

Evolution of RNA viruses occurs through disequilibria of collections of. .cle{Domingo2012ViralQE, title {Viral quasispecies evolution. The understanding of viruses as quasispecies has led to new antiviral designs, such as lethal mutagenesis, whose aim is to drive viruses toward low fitness values with limited chances of fitness recovery.

Domingo E (1997) RNA virus evolution, population dynamics, and nutritional status. Domingo E, Biebricher C, Eigen M, Holland JJ (2001) Quasispecies and RNA virus evolution: principles and consequences. Biol Trace Elem Res 56:23–30PubMedGoogle Scholar. Domingo E (1999) Quasispecies. Austin, Landes BioscienceGoogle Scholar. Domingo E, Ruíz-Jarabo CM, Arias A, Molina-Paris C, Briones C, Baranowski E, Escarmís C (2003) Detection and biological implications of genetic memory in viral quasispecies. by Esteban Domingo, John J. ISBN 9781587060106 (978-1-58706-010-6) Hardcover, R G Landes Co, 2001.

This book focuses on a new aspect of RNA virology: the highly dynamic, heterogeneous and plastic nature of RNA viruses which comprise more than 75% of the viruses that have been recognized as disease agents. It is the first attempt to bridge the gap from the basic, theoretical formulations underlying error-prone replications and generation of quasispecies, to their impact on how RNA viruses adapt and cause disease.
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