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eBook The Papovaviridae: The Papillomaviruses (The Viruses) ePub

by Peter M. Howley

Author: Peter M. Howley
Language: English
ISBN: 0306424525
ISBN13: 978-0306424526
Publisher: Springer; 1987 edition (June 30, 1987)
Pages: 408
Category: Medicine
Subcategory: Medical
Rating: 4.8
Votes: 939
Formats: lrf mobi rtf mbr
ePub file: 1158 kb
Fb2 file: 1444 kb

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eBook n/a. ISBN 978-1-4757-0584-3.

Very minimal writing or notations in margins not affecting the text. Possible clean ex-library copy, with their stickers and or stamp(s).

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Semantic Scholar extracted view of "The Papovaviridae" by Peter M Howley et a. oceedings{Howley1987TheP, title {The Papovaviridae}, author {Peter M Howley and N. P. Salzman and Helena Ahola}, booktitle {The Viruses}, year {1987} }. Peter M Howley, N. Salzman, +1 author Helena Ahola. Published in The Viruses 1987.

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In recent years there has been an explosion in research on the papillo maviruses. The viral nature of human warts was first suggested 80 years ago by Ciuffo, who demonstrated transmission using cell-free filtrates. Shope described the first papillomavirus over 50 years ago as the etiologic agent in infectious papillomatosis in rabbits. Subsequent studies by Rous established that benign rabbit papillomas induced by this virus could progress to carcinomas when treated with specific nonviral cofactors. Despite these rich beginnings, the papillomavirus field lay virtually dor mant until the late 1970s because no one was able to propagate these viruses in culture successfully. In the late 1970s the molecular cloning of the papillomavirus genomes permitted investigators to partially cir cumvent this obstacle to their progress. The cloning of the viral genomes permitted the standardization of viral reagents and provided sufficient material to begin a systematic evaluation of the biology of this group of viruses.