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eBook Non-Opioid Analgesics in the Treatment of Acute Pain: Johannesbergs Slott, Sweden, March 14, 1996 ePub

by Michael J Parnham

eBook Non-Opioid Analgesics in the Treatment of Acute Pain: Johannesbergs Slott, Sweden, March 14, 1996 ePub
Author: Michael J Parnham
Language: English
ISBN: 3764356804
ISBN13: 978-3764356804
Publisher: Birkhäuser; 1997 edition (June 16, 1997)
Pages: 21
Category: Medicine & Health Sciences
Subcategory: Other
Rating: 4.9
Votes: 671
Formats: mobi azw docx lit
ePub file: 1233 kb
Fb2 file: 1630 kb

9 Mode of action of dipyrone Professor K. Brune, M. D. Erlangen, Germany Most non-opioid analgesic drugs are inhibitors of cydo-oxygenase, the en­ zyme catalysing the formation of prostaglandins (PGs). Show all. Table of contents (8 chapters).

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book by Michael J. Parnham. Dipyrone is an antipyretic analgesic with an additional intrinsic spasmolytic activity.

Автор: Michael J Parnham Название: Non-Opioid Analgesics in the Treatment .

Johannesbergs Slott, Sweden, March 14, 1996. by Michael J Parnham

Johannesbergs Slott, Sweden, March 14, 1996. by Michael J Parnham.

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Pertinent guidelines recommend opioid-type analgesics for management of severe pain. However, in the past, opioids were prescribed for only a minority of these patients. In this representative study we examined the prevalence of cancer patients with and without opioid prescription in their final year of life in 1993 and 1996 in Bremen, Northern Germany. Complete four-months-samples of patients with cancer in Bremen were abstracted from the death certificates of 1993 and 1996

versatile analgesic drug with an overall risk of serious adverse events lower than most other non-opioid analgesics.

The results of these in vestigations have allayed the earlier concerns and have shown dipyrone to be a versatile analgesic drug with an overall risk of serious adverse events lower than most other non-opioid analgesics. Based on these results, the Swedish authorities (Lakemedelsverket) have approved the reintroduc tion of dipyrone to clinical use as a valuable contribution to pain treat ment.

Non-opioids in the treatment of post-operative pain. Comparative safety of non-opioid analgesics. oceedings{Parnham1997AreTM, title {Are the medical needs for the treatment of acute pain fulfilled?}, author {Michael John Parnham}, booktitle {Birkh{"a}user Basel}, year {1997} }. Michael John Parnham. Mechanisms of action of non-opioid analgesics. Fulfilling patients' needs for appropriate prescriptions: The acute pain service approach. Non-opioids in the treatment of post-operative pain.

Dipyrone is widely acknowledged to be an effective antipyretic analgesic with an additional intrinsic spasmolytic activity. It has stood the test of time over the last 75 years in many clinical settings throughout the world. Some 20 years ago, however, concern arose over the implications of isolat­ ed reports of agranulocytosis following use of dipyrone. Based on these initial cases the Swedish authorities ordered the withdrawal of the drug from the market. Subsequently, dipyrone has been subjected to extensive comparative epidemiological and clinical studies. The results of these in­ vestigations have allayed the earlier concerns and have shown dipyrone to be a versatile analgesic drug with an overall risk of serious adverse events lower than most other non-opioid analgesics. Based on these results, the Swedish authorities (Lakemedelsverket) have approved the reintroduc­ tion of dipyrone to clinical use as a valuable contribution to pain treat­ ment. In connection with this further milestone in the story of the drug, a symposium was held in Stockholm on March 14, 1996, under the chairman­ ship of Professor N. Rawal to review the current understanding of the ac­ tion, efficacy and safety of dipyrone. The highlights of this Hoechst symposium emphasize particularly the therapeutic basis for the use of dipyrone in the modern treatment of acute post-operative pain. 9 Mode of action of dipyrone Professor K. Brune, M. D. Erlangen, Germany Most non-opioid analgesic drugs are inhibitors of cydo-oxygenase, the en­ zyme catalysing the formation of prostaglandins (PGs).
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