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eBook The ABC Transporters of Human Physiology and Disease: Genetics and Biochemistry of ATP Binding Cassette Transporters ePub

by Kenneth J Linton,I Barry Holland

eBook The ABC Transporters of Human Physiology and Disease: Genetics and Biochemistry of ATP Binding Cassette Transporters ePub
Author: Kenneth J Linton,I Barry Holland
Language: English
ISBN: 9814280062
ISBN13: 978-9814280068
Publisher: World Scientific Pub Co Inc; 1 edition (September 22, 2011)
Pages: 451
Category: Medicine & Health Sciences
Subcategory: Other
Rating: 4.8
Votes: 449
Formats: lit lrf azw lrf
ePub file: 1331 kb
Fb2 file: 1392 kb

ATP Binding Cassette (ABC) transporters are a family of integral membrane proteins present in all cells of all species of. .

ATP Binding Cassette (ABC) transporters are a family of integral membrane proteins present in all cells of all species of archaea, eubacteria and eukaryota. The vast majority of these proteins control the transport across cellular membranes of molecules ranging from small ions to drugs, lipids and proteins.

ATP Binding Cassette (ABC) transporters are a family of integral membrane proteins present in all cells of all species of. This book - that brings together state-of-the-art knowledge on ABC proteins in one volume - will provide students, professors and medical professionals with a background to the human ABC transporters that are known to be relevant to disease.

ATP Binding Cassette (ABC) transporters are a family of integral membrane proteins that are likely . The human genome encodes 48 ABC transporters and most have been shown to underlie one or more human diseases.

ATP Binding Cassette (ABC) transporters are a family of integral membrane proteins that are likely to be represented in all the cells of all species of archaea, eubacteria and eukaryota. The vast majority of these proteins control the transport of molecules (from small hydrophilic ions to lipids and proteins) across cellular membranes.

ATP Binding Cassette (ABC) transporters are a family of integral .

ABC transporters are found in all known organisms, and approximately 1,100 different . ATP-Binding Cassette s. ATP-Binding Cassette ogy.

ABC transporters are found in all known organisms, and approximately 1,100 different transporters belonging to this family have been described in the literature. The family is defined by homology within the ATP-binding cassette (ABC) region, which extends outside of the more typical Walker motifs found in all ATP-binding proteins. The most common genetic disease conditions include cystic fibrosis, Stargardt disease, age-related macular degeneration,, Tangier disease, Dubin-Johnson syndrome and progressive familial intrahepatic cholestasis.

ATP-binding cassette or ABC transporters are a large superfamily of proteins found in all living organisms including bacteria, archaea, and eukarya. 22 These proteins typically transport a variety of compounds across cell membranes including drugs, ions, metabolites, lipids, vitamins, and organic compounds among others. ABC transporters have a core structure consisting of two transmembrane domains (TMDs) and two ABCs or nucleotide binding domains (NBDs). In prokaryotes, these domains can reside on individual polypeptides or fused onto larger polypeptides with the individual subunits assembling.

Kenneth J. Linton and I. Barry Holland . Keywords: Human physiology and disease, Disease management, Integral membrane proteins. Barry Holland,World Scientific Publishing Co Pte Ltd,2011,ISBN: 978-9-814-28006-8. ATP Binding Cassette (ABC) transporters are a family of integral membrane proteins that are likely to be represented in all the cells of all species of archaea, eubacteria and eukaryota.

This book provides students, professors and medical professionals with a background to the human ABC transporters that are known to be relevant to diseases.

Abc transporters of human physiology and disease Linton, Kenneth J. Holland, . arry World Scientific Publishing 9789814280068 : ATP Binding Cassette (ABC) transporters are a family of integra. This book provides students, professors and medical professionals with a background to the human ABC transporters that are known to be relevant to diseases.

Linton, Kenneth . Holland, I. EBSCO Publishing (Firm). ATP-binding cassette transporters. Clinical biochemistry Published: (2011).

The ABC transporters of human physiology and disease genetics and biochemistry of ATP binding cassette transporters /. Saved in.Linton, Kenneth . Engineering biosensors kinetics and design applications, by: Sadana, Ajit, 1947- Published: (2002). Biophysical approaches determining ligand binding to biomolecular targets Published: (2010). Carbohydrate binding modules functions and applications, by: Moreira, Susana.

The ATP-binding cassette (ABC) superfamily consists of membrane . Further characterization of all ABC genes from humans and model organisms will lead to additional insights into normal physiology and human disease. Download full-text PDF. Source.

The ATP-binding cassette (ABC) superfamily consists of membrane proteins that transport a wide variety of substrates across membranes.

ATP Binding Cassette (ABC) transporters are a family of integral membrane proteins present in all cells of all species of archaea, eubacteria and eukaryota. The vast majority of these proteins control the transport across cellular membranes of molecules ranging from small ions to drugs, lipids and proteins. The human genome encodes 48 ABC transporter genes and mutations in most have been linked to disease. This book — that brings together state-of-the-art knowledge on ABC proteins in one volume — will provide students, professors and medical professionals with a background to the human ABC transporters that are known to be relevant to disease. Each of the 14 chapters is written by a leading researcher in the field. The genetics, structure and function of the proteins, and the future direction of research including the implications for human health are discussed in depth.
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